Nanaka hadn't thought the large creature fast enough to block her strikes. Especially given its tendency for aggression, but perhaps the smaller familiar was guiding it. Which seems more likely given their master's preoccupation.
As a result, the spell strikes her, making her thoughts come out as a bit clouded and muddled. Nanaka clutches her head, or rather she reaches towards the gemstone that decorates it. She;d been holding it in for a while, but without her proper presence of mind, she wouldn't be able to hold it any longer.
As the smaller creature tosses a bottle at Nanaka, a single woody vine laced with brambles lashes out to strike it. Though the plant catches alight, the limb is soon devoured, the fire absorbed with it as Nanaka's body goes limp.
This is the last thing the other three would be able to see, as both Nanaka and the two minions seem to vanish into thin air. In reality, Nanaka's body goes limp as Duplicity takes shape, its thorns carelessly tearing through the girl's body as a field of flowers blooms out around her, surrounding both Nanaka and the familiars in a barrier of her own design.
The brambles unite and condense in the air over Nanaka, unfurling into a curtain through which only vague glimpses can be seen.
Now there was a beautiful world of Duplicity's making, sullied only by the disgusting creatures whose very foundation was poison. Seeking to remove this blemish, Duplicity acts as it always has, creating a thicket of thorns to choke out the area around the larger familiar, making any movement on its part difficult and painful.
With the flying creature being met by a trio of vines, which try to work together in hopes of cornering and grappling the familiar to drain it of its very being.